Table 1.
Outcomes at 6-month and 12-month follow-up
| Variable | 6-month outcomes |
12-month outcomes |
||||||||
| Groups based on categorical outcomes at the end of active trial at 12 weeks |
Statistic and signif. | Groups based on categorical outcomes at the end of active trial at 12 weeks |
Statistic and signif. | |||||||
| Overall (N = 54) | Full resp. (n = 25) | Partial resp. (n = 22) | Nonresp. (n = 7) | Overall (N = 50) | Full resp. (n = 22) | Partial resp. (n = 21) | Nonresp. (n = 7) | |||
| Overall outcomes % full responders | 40.7% | 68.0% | 13.6% | 28.6% | χ2=19.9, 4df, p = .001a | 42.0% | 63.6% | 33.3% | 0.0% | χ2 = 11.7, 4df, p = .020a |
| Drinking outcomes % Relapsed to heavy drinking | 38.9% | 12.0% | 59.1% | 71.4% | χ2=14.5, 2df, p <.001a | 34.0% | 18.2% | 28.6% | 100% | χ2=16.3, 2df, p = .001a |
| Proportion of heavy drinking days | 0.1 (0.3) | 0.0 (0.2) | 0.1(0.2) | 0.4 (0.4) | F = 8.2, 2df, p = .001 | 0.2 (0.3) | 0.1(0.3) | 0.1(0.2) | 0.5(0.4) | F = 7.04, 2df, p = .002 |
| Depression outcomes % Depressed (HAM-D ≥ 10) | 46.3% | 24.0% | 68.2% | 57.1% | χ2= 9.6, 2df, p = .008a | 40.0% | 27.3% | 52.4% | 42.9% | χ2 = 2.85, ns |
| HAM-D scores | 11.1 (7.3) | 7.1 (5.4) | 14.7 (6.8) | 14.1 (8.3) | F = 9.2, 2df, p < .001 | 11.8 (9.1) | 8.8 (7.0) | 14.2 (9.9) | 14.3 (10.8) | F = 2.37, ns |
Notes: For categorical variables, frequencies are shown in percentages. For continuous variables, values are shown as mean (SD). All outcomes based on information obtained for 30 days before the 12-week, 6-month, and 12-month visit. Resp. = responders; nonresp. = nonresponders; signif. = significance; HAM-D = Hamilton Rating Scale for Depression; ns = not significant.
a
Indicates that certain individual cells had numbers less than the minimum required for chi-square analysis.