Fig. 1.

The architecture of the model. (A) Overview of the model shows 3 stages: peripheral inputs in five groups, dendritic filtering and summation, followed by a MacGregor integrate and fire model of spiking. Five groups of input fibers originate from contiguous channels of the AN model, each with different BFs. Each group innervates a different location on the cell dendrites. (B) A single group within the peripheral stage consisting of a bandpass middle ear function, several channels of the basilar membrane model at different contiguous points, and an IHC for each channel. For each channel n auditory nerve fiber inputs are generated depending on the model parameters, and the resulting impulses filtered to resemble post-synaptic potentials. (C) Schematic of the parametric variation of AN inputs. Each group of inputs is varied independently. The parameters are the BF range of each group and the density of fibers. (D) Example voltage trace from the MacGregor neuron under current injection at depolarizing (upper voltage trace showing spike generation) and hyperpolarizing (lower voltage trace) current values. The time course of current injection is shown separately below the voltage traces.