Figure 4.

Hazard ratio (HR) and 95% confidence interval (CI) estimates for the associations between: (1) the mean monthly percentage change in EPO dose during the sub-11 period (months 4 to 6) and the risk of death over the follow-up period (left panel); and (2) the month-6 achieved Hb level and the risk of death over the follow-up (right panel). This analysis was limited to patients who were receiving the highest maintenance EPO doses (upper tertile) in the last month of the entry period (month 3). Estimates were adjusted for age, race, gender, body mass index, diabetes, vascular access type, albumin, ferritin, transferrin saturation, systolic and diastolic blood pressure, missed EPO administrations, iron dose, and hospitalizations.