Table 1.

Overview of study populations

Major Comorbidity	Trial Population	Trial Name
Renal failure, candidates for renal transplantation	26 subjects age ≥60 yr	Physical Function and Quality of Life in Older Candidates for Kidney Transplantation
Diastolic heart failure	71 subjects age ≥65 yr	Pharmacologic Intervention in the Elderly (PIE)
Chronic obstructive pulmonary disease	176 subjects age 55 to 80 yr	The Reconditioning Exercise and Chronic Obstructive Pulmonary Disease Trial II (REACT II) (21)
High risk for cardiovascular disease	294 subjects >55 to 80 yr of age	Trial of Angiotensin Converting Enzyme Inhibition and Novel
		Cardiovascular Risk Factors (TRAIN) (22)