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. 2009 Mar;20(3):535–544. doi: 10.1681/ASN.2008040377

Figure 2.

Figure 2.

The CX3CR1 pathway and formation of heart tissue DC. (A and B) Compared with CX3CR1−/− hearts (B), naive WT hearts (A) contain a much greater percentage and number of DC. DC were counted per 20 sections of naive heart tissue and were 75 ± 5 and 43 ± 4 for WT and CX3CR1−/−, respectively (n = 3 mice/group; P < 0.02). Sections of naive hearts were immunostained for CD11c. CD11c+ cells (red) co-localized with endothelial cells (stained with anti-CD31 FITC, green) were identified in WT and CX3CR1−/− hearts.