Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Mar;20(3):489–494. doi: 10.1681/ASN.2008050503

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2009 by the American Society of Nephrology

PMC Copyright notice

Figure 3. — Albumin distribution in PT cells is reduced in diabetes. (A) Representative pictures of the distribution of albumin in the kidney of 12-wk diabetic rats and age-matched control rats. Images shown are before albumin-Alexa568 (red) injection and 2.5 min and 24 min after albumin-Alexa injection. Albumin uptake (red) can be seen in the S1 segment of the PT (arrows). This uptake is dramatically reduced in the diabetic group. Bar = 30 μm. (B) Enlarged picture of the region highlighted by arrows in A. The enlarged picture demonstrates the dramatic change in the distribution of albumin in PT cells. Bar = 15 μm. (C) Quantification of the amount of albumin distributed along the S1 segment throughout the cell (P < 0.01 control versus diabetic; control n = 4, diabetic n = 4). G, glomerulus; PT, proximal tubule.