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Effect of HG on BMP-7 production of HPMCs. (A) HG (60 mM/L d-glucose) induced a decrease in BMP-7 mRNA expression from 12 to 48 h. (B and C) HG also decreased the production of BMP-7 protein at 48 h assessed by Western blotting (B) and ELISA (C). n = 5. *P < 0.05 versus control at each time point.
