Figure 9.

Effect of rHGF on HG-induced EMT of HPMCs. (A through C) rHGF ameliorated HG-induced alteration in mRNA expressions of E-cadherin (A) and α-SMA, fibronectin, and type I collagen from a dosage of 20 ng/ml at 48 h (B) and 7 d (C) of treatment. (D) Representative Western blotting shows an amelioration of HG-induced changes in E-cadherin and α-SMA with 20 ng/ml rHGF. n = 6 for real-time PCR, and n = 5 for Western blotting. *P < 0.05 versus NG at each time point; †P < 0.05 versus HG at each time point.