. Author manuscript; available in PMC: 2009 Dec 1.

Published in final edited form as: Psychiatr Genet. 2008 Dec;18(6):267–274. doi: 10.1097/YPG.0b013e3283060f59

Table 1.

BDNF SNPs: chromosome position, minor allele frequency and association with bipolar disorder

					Average PDT^c
SNP #	SNP	Position^a	Location^†	MAF^b	Model 1	Model 2	Model 3
1	rs1519480	27,632,288	downstream	0.30	0.005	0.02	0.03
2	rs6265	27,636,492	exon 2Val66met	0.21	0.40	0.26	0.06
3	rs11030104	27,641,093	intron 1	0.22	0.78	0.87	0.35
4	rs7103411	27,656,701	intron 1	0.23	0.64	0.69	0.27
5	rs7127507	27,671,460	intron 1	0.32	0.002	0.009	0.009
6	rs988748	27,681,321	intron 1	0.23	0.55	0.58	0.21
7	rs2030324	27,683,491	intron 1	0.47	0.02	0.04	0.16
8	rs7934165	27,688,559	intron 1	0.49	0.12	0.24	0.58
9	rs2883187	27,697,668	intron 1	0.47	0.02	0.04	0.14
10	rs12273363	27,701,435	upstream	0.20	0.05	0.12	0.10

Positions along Chromosome 11 are based on dbSNP build 125/human genome build 34.1.

^†

Position within or near gene

Minor allele frequency in European Americans in this study

P-value of Average PDT statistic for association between the SNPs and bipolar disorder. Significantly associated SNPs are shown in bold. Analyses are reported for the narrow definition of unaffected in which everyone who is not affected is classified as unknown rather than unaffected.