. Author manuscript; available in PMC: 2010 Feb 1.

Published in final edited form as: DNA Repair (Amst). 2008 Dec 5;8(2):182–189. doi: 10.1016/j.dnarep.2008.10.006

Table 4. ENEYP misincorporates dGTP opposite template A.

		k_pol (sec^-1)	K_d (M)	k_pol/ K_d (sec^-1 M^-1)	Fidelity^a	WT/ENEYP
WT	dT:A^b	1.58 0.080	58.9 13.5	26874.1
	dG:A	0.0048 0.00020	390.8 58.0	12.1	2211
	dC:A	0.00473 0.00026	327.9 66.8	14.4	1867.3
	dA:A	0.00378 0.00012	288.8 36.6	13.1	2055.6
ENEYP	dT:A	1.20 .038	83.7 8.25	14382.5
	dG:A	0.00315 0.00011	84.8 14.0	37.1	388.8	5.69
	dC:A	0.00681 0.00037	340.7 67.3	20	720.1	2.59
	dA:A	0.00304 0.00010	178.5 25.5	17.1	844.5	2.43

Fidelity is calculated as described in Methods and Materials.

The templating base is underlined.