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. Author manuscript; available in PMC: 2009 Mar 10.
Published in final edited form as: Circ Res. 2008 May 1;102(11):1406–1415. doi: 10.1161/CIRCRESAHA.107.170050

Figure 2. Alterations in repolarizing K+ currents in TAC LV myocytes.

Figure 2

Representative whole-cell Kv currents (A), evoked during 4.5-second voltage steps to potentials between −40 and +40 mV from a holding potential (HP) of −70 mV, and Kir currents (B), evoked during 350-ms voltage steps to potentials between −40 and −120 mV (HP=−70 mV) in sham and TAC LV cells. Mean±SEM Ipeak (C), Ito,f (D), IK,slow (E), Iss (F), and IK1 (G) densities in sham and TAC LV myocytes are plotted as a function of test potential. Relative changes in Cm (H), current amplitudes (I), and densities (J) in TAC compared with sham LV myocytes. Values in TAC and sham LV myocytes are significantly (*P<0.001, #P<0.01) different.