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. 2008 Oct;43(5 Pt 1):1557–1575. doi: 10.1111/j.1475-6773.2008.00858.x

Table 3.

Savings Achieved by Switching to Best Buy Drugs, by Class, in 2006

ACE Inhibitors Beta Blockers Calcium Channel Blockers Statins Total





Dollars (in Millions) % Dollars (in Millions) % Dollars (in Millions) % Dollars (in Millions) % Dollars (in Millions) %
Actual sales in 2005 $3,855.77 $5,232.08 $5,282.09 $20,881.85 $35,251.79
Savings possible
100% of substitutions achieved $280.13 7.3 $213.84 4.1 $1,015.16 19.2 $1,249.80 6.0 $2,758.93 7.8
50% of substitutions achieved $140.07 3.6 $106.92 2.0 $507.58 9.6 $624.90 3.0 $1,379.47 3.9
25% of substitutions achieved $70.03 1.8 $53.46 1.0 $253.79 4.8 $312.45 1.5 $689.73 2.0
Distribution of savings
% from generic substitution 14.9 96.5 22.5 56.0 0.0
% from therapeutic substitution 85.1 3.5 77.5 44.0 0.0