Table 4.
The effects of component measures of the host immune response on the survivorship and fecundity of Strongyloides ratti
| Term | Coefficient | χ2 | P-value | |
|---|---|---|---|---|
| Survivorshipa | Constant | −1.652 ± 0.25 | ||
| IgG1 | −0.17 ± 0.035 | 35.55 | <0.0001 | |
| IgA | −8.8 ± 2.1 | 11.72 | 0.0006 | |
| IL-4 MLN | 0.018 ± 0.005 | 11.07 | 0.0009 | |
| IL-4 MLN2 | −5.7 × 10−5 ± 2.3 × 10−5 | 5.54 | 0.0185 | |
| Time | −0.08 ± 0.024 | 10.7 | 0.001 | |
| Fecundityb | Constant | 3.43 ± 0.83 | ||
| IgA | 45.61 ± 15.3 | 6.11 | 0.013 | |
| IgA2 | −361.74 ± 140.5 | 4.3 | 0.038 | |
| Time | 0.018 ± 0.046 | 0.124 | 0.724 | |
| ln Adults | 1.38 ± 0.36 | 11.25 | 0.0008 | |
| Time * ln Adults | −0.11 ± 0.02 | 15.07 | 0.0001 |
IgG1, mean = 3.13, range = 0–41.72; IgA, mean = 0.022, range = 0–0.12; IL-4, mean = 29.95, range = 0–211.7.
a
Response variable = number of parasitic females; offset variable = ln Dose; 2 × log-likelihood = −151.9, k = 16.5.
b
Response variable = total viable egg output of parasitic females; offset variable = ln Adults; 2 × log-likelihood = −415.9, k = 1.633.