TABLE 1.
Inhibition of ICOS-Induced PI-3K Activity Promotes T Cell Migration
| Total distance (μm) | Distance from origin (μm) | Velocity (μm/s) | |
|---|---|---|---|
| No inhibitor | 35.5 ± 49.60a | 3.84 ± 3.00b | 0c |
| Wortmannin | 378.8 ± 80.04 | 66.2 ± 49.84 | 0.124 ± 0.026 |
a
Average total distance traveled by individual cells over 250 frames taken at 15 s intervals. All calculations were an average of 20 individual cell migration patterns for each treatment group.
b
Average distance between where a cell was located at the start of filming (Frame 1) to where it was located after 250 frames.
c
Average velocity of individual cells during their 250 frames of filming.