Table 1. Distribution of genotypes and allelic frequencies.
| TNF-α single nucleotide polymorphism | Patients with XFG (n=204) | Control subjects (n=204) | Significance p-value |
|---|---|---|---|
|
TNF-α –308GG |
152 (74.5) |
151 (74.0) |
0.91 |
| –308GA |
48 (23.5) |
51 (25.0) |
0.73 |
| –308AA |
4 (2.0) |
2 (1.0) |
0.41 |
|
TNF-α –308 G allele frequency |
0.863 |
0.865 |
0.92 |
|
TNF-α –238GG |
182 (89.2) |
189 (92.6) |
0.23 |
| –238GA |
21 (10.3) |
15 (7.4) |
0.30 |
| –238AA |
1 (0.5) |
- |
- |
| TNF-α –238 G allele frequency | 0.944 | 0.963 | 0.18 |
Distribution of TNF-α –308 G>A and TNF-α –238 G>A genotypes and allelic frequencies in patients with exfoliation glaucoma and control subjects in an European population of Caucasian descent. Numbers for genotypes are n (%).