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Metabolic consequences of high fat diet and icv TLQP-21 treatment. The figure shows food intake (a), body weight gain (b), metabolic efficiency (c) and weight of the epididymal white adipose tissue (d) in mice fed a standard (SD) or a high fat diet (HFD) and chronically intracerebroventricularly injected with artificial cerebrospinal fluid (aCSF) or TLQP-21. ** and §§P < 0.01, * and §P < 0.05 versus SD-aCSF and versus HFD-aCSF, respectively
