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. 2009 Mar 17;4(3):e4868. doi: 10.1371/journal.pone.0004868

Table 1. G+C content shows correlation with polysome shift for total mRNA, coding and 3′UTR but not for 5′UTR sequence.

eIF4E AKT
p-Value Correlation Coefficient p-Value Correlation Coefficient
Total mRNA <2.2·10−16 0.3848 <2.2·10−16 0.2141
5′UTR <2.2·10−16 0.1196 8.47·10−12 0.0788
Coding <2.2·10−16 0.3535 <2.2·10−16 0.1677
3′UTR <2.2·10−16 0.3232 <2.2·10−16 0.1691

Table shows G+C content of mRNA (total mRNA or 5′UTR, coding, 3′UTR) as a function of fold change. P-values and correlation coefficients are computed according to the Spearman correlation for the eIF4E overexpression data set (11387 mRNAs) and the AKT activation data set (7496 mRNAs).