Table 5. Highly upregulated mRNAs show mostly negative selection (site avoidance) for miRNA binding sites.
| Name | upreg+ | upreg− | nonreg+ | nonreg− | p-value | ratio |
| miR-589 | 9 | 31 | 651 | 549 | 0.00008 | 0.41 |
| miR-507 | 3 | 37 | 373 | 827 | 0.00070 | 0.24 |
| let-7i | 6 | 34 | 494 | 706 | 0.00082 | 0.36 |
| miR-571 | 4 | 36 | 408 | 792 | 0.00095 | 0.29 |
| miR-647 | 8 | 32 | 549 | 651 | 0.00109 | 0.44 |
| miR-766 | 13 | 27 | 706 | 494 | 0.00162 | 0.55 |
| miR-18b | 7 | 33 | 507 | 693 | 0.00164 | 0.41 |
| miR-644 | 9 | 31 | 572 | 628 | 0.00188 | 0.47 |
| miR-622 | 10 | 30 | 601 | 599 | 0.00197 | 0.50 |
| let-7g | 7 | 33 | 487 | 713 | 0.00286 | 0.43 |
| miR-363* | 7 | 33 | 484 | 716 | 0.00296 | 0.43 |
| miR-452* | 9 | 31 | 559 | 641 | 0.00320 | 0.48 |
| miR-18a | 8 | 32 | 516 | 684 | 0.00326 | 0.47 |
| miR-27b | 10 | 30 | 585 | 615 | 0.00341 | 0.51 |
| miR-550 | 5 | 35 | 409 | 791 | 0.00341 | 0.37 |
| let-7f | 7 | 33 | 481 | 719 | 0.00454 | 0.44 |
| miR-98 | 7 | 33 | 469 | 731 | 0.00482 | 0.45 |
| miR-636 | 9 | 31 | 532 | 668 | 0.00574 | 0.51 |
| miR-502 | 10 | 30 | 568 | 632 | 0.00575 | 0.53 |
| miR-642 | 13 | 27 | 658 | 542 | 0.00590 | 0.59 |
| miR-330 | 12 | 28 | 629 | 571 | 0.00591 | 0.57 |
| miR-379 | 4 | 36 | 346 | 854 | 0.00704 | 0.35 |
| miR-30e-3p | 8 | 32 | 494 | 706 | 0.00809 | 0.49 |
| let-7d | 8 | 32 | 493 | 707 | 0.00812 | 0.49 |
| let-7b | 8 | 32 | 486 | 714 | 0.00848 | 0.49 |
| miR-27a | 10 | 30 | 554 | 646 | 0.00922 | 0.54 |
| miR-331 | 6 | 34 | 417 | 783 | 0.01010 | 0.43 |
| miR-488 | 6 | 34 | 413 | 787 | 0.01019 | 0.44 |
| let-7a | 8 | 32 | 476 | 724 | 0.01283 | 0.50 |
| let-7c | 8 | 32 | 476 | 724 | 0.01283 | 0.50 |
| miR-30a-3p | 9 | 31 | 507 | 693 | 0.01383 | 0.53 |
| miR-335 | 9 | 31 | 507 | 693 | 0.01383 | 0.53 |
| miR-652 | 6 | 34 | 400 | 800 | 0.01563 | 0.45 |
| miR-93 | 14 | 26 | 654 | 546 | 0.01588 | 0.64 |
| miR-489 | 8 | 32 | 468 | 732 | 0.01950 | 0.51 |
| miR-199a* | 8 | 32 | 461 | 739 | 0.01965 | 0.52 |
List of miRNAs with negative selection (avoidance of binding sites) among 40 highly eIF4E upregulated mRNAs (fold change greater 4.0) and 1200 nonregulated mRNAs (fold change between 1.05 and 1.0/1.05). upreg+: number of upregulated mRNAs that show positive selection with respect to the specified miRNA, upreg−: number of upregulated mRNAs with negative selection, nonreg+: number of nonregulated mRNAs with positive selection of miRNA-target binding sites; nonreg−: number of nonregulated mRNAs with negative selection. P-values are computed according using a Fisher exact test, all entries with a p-value smaller than 0.02 are listed. Ratio: (upreg+/(upreg++upreg−))/(nonreg+/(nonreg++nonreg−)).