Table 6. A few upregulated mRNAs show positive selection for miRNA binding sites.

Name	upreg+	upreg−	nonreg+	nonreg−	p-value	ratio
miR-217	25	15	383	817	0.00011	1.96
miR-656	26	14	406	794	0.00013	1.92
miR-375	22	18	366	834	0.00162	1.80
miR-126*	20	20	316	884	0.00178	1.90
miR-545	25	15	459	741	0.00271	1.63
miR-607	25	15	460	740	0.00275	1.63
miR-194	26	14	483	717	0.00280	1.61
miR-374	22	18	401	799	0.00631	1.65
miR-598	22	18	405	795	0.00677	1.63
miR-220	20	20	347	853	0.00730	1.73
miR-631	22	18	413	787	0.01069	1.60
miR-325	16	24	266	934	0.01207	1.80
miR-802	24	16	474	726	0.01304	1.52

List of miRNAs with positive selection (accumulation of binding sites) among 40 highly eIF4E upregulated mRNAs (fold change greater 4.0) and 1200 nonregulated mRNAs (fold change between 1.05 and 1.0/1.05). See caption of Table 5 for an explanation of table columns.