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. 2009 Mar 13;4(3):e4761. doi: 10.1371/journal.pone.0004761

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Rigola et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The top panel shows numbers of G to A (position 221) and C to T (position 170) sequence deviations compared to the wild type sequence observed in each of the 3D pools in a subset of nucleotide positions of the SleIF4E amplicon 1. The total number of observed sequence deviations and calculated average error rates are shown at the right hand side. The bottom panel shows corresponding P values of false positives for each X, Y and Z pool. Total numbers of pools surpassing significance thresholds P<0.001, P<0.01 and P<0.05 are shown at the bottom right. The complete analysis of all nucleotide positions are shown in figure S4.