TABLE II.
Ca2+ (μM) | αWT | αD369G | αWTβ4 | αD369Gβ4 | ||||||||
V1/2 (mV) | Q (e0) | n | V1/2 (mV) | Q (e0) | n | V1/2 (mV) | Q (e0) | n | V1/2 (mV) | Q (e0) | n | |
0.006 | 177.6 ± 4.0 | 1.30 ± 0.06 | 12 | 161.5 ± 2.5 | 1.23 ± 0.05 | 14 | 246.1 ± 3.8 | 0.81 ± 0.23 | 4 | 237.2 ± 12.2 | 0.66 ± 0.05 | 9 |
0.073 | 162.5 ± 5.2 | 1.53 ± 0.12 | 13 | 126.2 ± 3.0 | 1.63 ± 0.11 | 9 | 206.4 ± 9.7 | 1.16 ± 0.16 | 6 | 150.9 ± 3.74 | 1.34 ± 0.13 | 9 |
0.363 | 130.2 ± 3.8 | 1.63 ± 0.11 | 15 | 85.6 ± 4.3 | 1.77 ± 0.14 | 16 | 155.8 ± 6.2 | 1.33 ± 0.10 | 19 | 111.0 ± 3.8 | 1.84 ± 0.12 | 10 |
2.1 | 57.3 ± 3.1 | 1.93 ± 0.08 | 26 | 16.2 ± 3.1 | 2.06 ± 0.09 | 22 | 74.5 ± 5.6 | 1.54 ± 0.06 | 19 | 40.2 ± 3.6 | 1.62 ± 0.05 | 32 |
41 | −15.7 ± 2.5 | 1.85 ± 0.09 | 19 | −34.3 ± 3.6 | 1.63 ± 0.08 | 18 | −36.9 ± 2.8 | 1.88 ± 0.04 | 38 | −65.6 ± 2.7 | 1.77 ± 0.13 | 15 |
The values shown are Boltzmann-fit parameters. They indicate mean ± sem.