Figure 4. The effects of C26 tumor on development of cachexia (defined as loss of more than 5% of body weight (BW) after inoculation of tumor cells) in mice.

(A) Left panel: Kaplan-Meyer plot for Vehicle control (dashed black line), Vehicle+Tumor control (black line), and SNT207707 30 mg/kg (grey line) group (n = 9 each). (B) Right panel: Kaplan-Meyer plot for Vehicle control (dashed black line), Vehicle+Tumor control (black line), and SNT207858 30 mg/kg (grey line) group (n = 9 each). Note: Statistical comparison between Vehicle+Tumor and treatment groups was significant.