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. 2009 Mar 17;4(3):e4924. doi: 10.1371/journal.pone.0004924

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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A. Space-filled diagram of the three-dimensional model of the complete BoNT/A holotoxin showing the heavy (dark gray) and light (light gray) chains. QPDRS motif is the colored region within the light chain. B. Enlarged view of Q139 (red), P140 (blue), D141 (yellow), R145 (green) and S146 (pink) [7].