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. Author manuscript; available in PMC: 2009 Mar 11.
Published in final edited form as: Biochemistry. 2006 Jul 4;45(26):8079–8087. doi: 10.1021/bi060189c

Figure 5. A single point mutation that optimizes tRNAAsp specificity is less toxic when expressed in E. coli.

Figure 5

Wild-type and mutant AspRS were each evaluated for toxicity arising from heterologous expression in E. coli, as in Figure 1. Error analysis represents the average ≥3 repetitions of each experiment.