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. Author manuscript; available in PMC: 2009 Mar 11.
Published in final edited form as: Gastroenterology. 2008 Nov 1;136(3):1048–1059. doi: 10.1053/j.gastro.2008.10.027

Figure 4. Increased accumulation of neutrophils in the cholestatic livers of NKT cell-deficient mice.

Figure 4

A. The hepatic leukocyte populations were obtained at 18 hours post-BDL and the percentages of Ly-6G+CD11b+ neutrophils (upper right quadrant) constituting the population derived from wild-type (left panels) and Jα18−/− (right panels) mice were determined by flow cytometric analyses. B. The livers of wild-type (left) and iNKT cell-deficient (right) mice were dissected on day 3 following sham-operation (top) or bile duct ligation (bottom). Fixed and paraffin-embedded tissue samples were sectioned and the presence of neutrophils (distinguished by brown precipitate) was assessed by immunohistochemical staining (original 100x magnification). Two experiments yielded comparable results.