Table 3.
Results of multivariate multinomial logistic regression (RRR with 95%CI). Correlates of increased APRI in a cohort of HIV/HCV coinfected individuals, adjusted for age and self-reported race. Reference category is APRI<0.4. n=662.
| Participant Characteristic | Unadjusted RRR for RRR for 0.4<APRI<1.5 |
Adjusted RRR for 0.4<APRI<1.5 |
Unadjusted RRR for APRI>1.5 |
Adjusted RRR for APRI>1.5 |
|---|---|---|---|---|
| Gender | ||||
| Female | 1.00 | 1.00 | 1.00 | 1.00 |
| Male | 1.66 (1.16-2.38) | 1.78 (1.20-2.65) | 1.59 (0.99-2.54) | 1.56 (0.93-2.61) |
| HIV transmission category IDU? | ||||
| No | 1.00 | 1.00 | 1.00 | 1.00 |
| Yes | 1.66 (1.09-2.54) | 1.56 (1.00-2.43) | 1.91 (1.06-3.45) | 1.85 (0.77-4.27) |
| HbSAg + | ||||
| No | 1.00 | 1.00 | 1.00 | 1.00 |
| Yes | 1.34 (0.66-2.74) | 1.11 (0.53-2.33) | 2.00 (0.88-4.55) | 1.81 (0.77-4.27) |
| CD4 nadir | ||||
| ≤50 | 1.00 | 1.00 | 1.00 | 1.00 |
| 51-200 | 0.91 (0.58-1.42) | 0.91 (0.61-1.54) | 1.18 (0.68-2.07) | 1.26 (0.71-2.25) |
| 201-350 | 0.56 (0.34-0.92) | 0.63 (0.38-1.05) | 0.73 (0.39-1.37) | 0.78 (0.40-1.49) |
| >350 | 0.48 (0.29-0.81) | 0.48 (0.27-0.84) | 0.34 (0.15-0.75) | 0.31 (0.13-0.72) |
| HIV RNA <400 | ||||
| No | 1.00 | 1.00 | 1.00 | 1.00 |
| Yes | 0.74 (0.52-1.05) | 0.72 (0.49-1.05) | 0.66 (0.41-1.05) | 0.64 (0.39-1.05) |
| Alcohol category | ||||
| 0 (no consumption) | 1.00 | 1.00 | 1.00 | 1.00 |
| 1 (non-hazardous) | 0.87 (0.55-1.36) | 0.79 (0.49-1.27) | 1.21 (0.69-2.11) | 1.11 (0.61-2.01) |
| 2 (hazardous) | 1.70 (0.93-3.14) | 1.89 (0.98-3.66) | 1.95 (0.93-4.10) | 2.05 (0.91-4.62) |
Abbreviations: IDU, injection drug use; HBSAg, hepatitis B surface antigen.
Alcohol categories: 0, no alcohol consumption; 1, no more than 14 drinks per week and no more than 4 drinks per occasion for men or no more than 7 drinks per week and no more than 3 drinks per occasion for women; 2, more than 14 drinks per week or more than 4 drinks per occasion for men or more than 7 drinks per week or more than 3 drinks per occasion for women.