Table 4.

Results of multivariate multinomial logistic regression (RRR with 95%CI). Correlates of increased APRI in HIV-infected patients without HCV infection, adjusted for age and self-reported race. Reference category is APRI<0.4. n=697.

Participant Characteristic	Unadjusted RRR for RRR for 0.4<APRI<1.5	Adjusted RRR for 0.4<APRI<1.5	Unadjusted RRR for APRI>1.5	Adjusted RRR for APRI>1.5
Gender
Female	1.00	1.00	1.00	1.00
Male	1.61 (1.09-2.36)	1.45 (0.95-2.21)	1.22 (0.60-2.49)	1.48 (0.66-3.30)
HIV transmission category IDU?
No	1.00	1.00	1.00	1.00
Yes	1.67 (0.98-2.85)	1.92 (1.10-3.35)	2.85 (1.23-6.62)	3.85 (1.49-9.97)
HbSAg +
No	1.00	1.00	1.00	1.00
Yes	2.35 (1.32-4.17)	2.06 (1.13-3.75)	4.20 (1.77-9.99)	3.57 (1.36-9.33)
CD4 nadir
≤50	1.00	1.00	1.00	1.00
51-200	0.68 (0.44-1.04)	0.67 (0.43-1.06)	0.66 (0.29-1.49)	0.79 (0.32-1.91)
201-350	0.68 (0.42-1.09)	0.63 (0.38-1.04)	0.83 (0.36-1.92)	0.89 (0.35-2.25)
>350	0.51 (0.28-0.92)	0.43 (0.23-0.80)	0.13 (0.02-1.03)	0.13 (0.02-1.00)
HIV RNA <400
No	1.00	1.00	1.00	1.00
Yes	0.64 (0.45-0.91)	0.61 (0.42-0.89)	0.17 (0.07-0.41)	0.17 (0.07-0.44)
Alcohol category
0 (no consumption)	1.00	1.00	1.00	1.00
1 (non-hazardous)	1.30 (0.88-1.93)	1.21 (0.80-1.85)	0.54 (0.20-1.45)	0.53 (0.18-1.49)
2 (hazardous)	1.50 (0.83-2.71)	1.69 (0.91-3.14)	2.69 (1.13-6.39)	3.72 (1.40-9.87)

Abbreviations: RRR, relative risk ratio; 95%CI, 95% confidence interval; APRI, aspartate aminotransferase to platelet ratio index; IDU, injection drug use..

Alcohol categories: 0, no alcohol consumption; 1, no more than 14 drinks per week and no more than 4 drinks per occasion for men or no more than 7 drinks per week and no more than 3 drinks per occasion for women; 2, more than 14 drinks per week or more than 4 drinks per occasion for men or more than 7 drinks per week or more than 3 drinks per occasion for women.