Table 3. Haplotype analysis for risk of Parkinson disease in the GenePD Study.
hCV3202946 | rs1800547 | rs3785883 | rs2435207 | rs11568305 | rs1078997 | Freq. PD | Freq. C | OR | p Value |
---|---|---|---|---|---|---|---|---|---|
1 | 2 | 1 | 1 | 1 | 1 | 0.13 | 0.23 | 0.63 | 0.01* |
1 | 1 | 1 | 1 | 1 | 1 | 0.41 | 0.41 | 1.00 | |
1 | 1 | 1 | 2 | 1 | 1 | 0.17 | 0.16 | 1.04 | 0.84 |
1 | 1 | 2 | 2 | 1 | 1 | 0.067 | 0.017 | 4.48 | 0.003* |
Haplotypes present in less than 5% of the population are not shown in this table. The major allele is denoted as 1 and the minor allele as 2. Freq. PD = haplotype frequency in Parkinson disease cases; Freq. C = haplotype frequency in controls; OR = odds ratio. Global p value 0.003.
Significant.