Table 1.
Multivariate (Cox model) Analysis of Clinical and Pathologic Predictors of Systemic Progression After Radical Retropubic Prostatectomy From the Mayo Clinic Radical Retropubic Prostatectomy Database of Men (N = 10,626)
| Variable | Gleason Score
|
|||
|---|---|---|---|---|
| All
|
7-10
|
|||
| Hazard Ratio | P | Hazard Ratio | P | |
| Gleason | ||||
| 7 | 4.0* | < .0001 | NA | — |
| 8-10 | 8.5* | < .0001 | 2.2† | < .0001 |
| Extracapsular extension | 1.7 | < .0001 | 1.2 | .26 |
| Seminal vesicle involvement | 2.9 | < .0001 | 2.6 | < .0001 |
| Nodal involvement | 1.6 | .002 | 1.5 | .030 |
| Adjuvant hormone therapy | 0.7 | .005 | 0.8 | .076 |
| No. of patients | 10,626 | 3,636 | ||
| No. of events | 441 | 335 | ||
| Concordance statistic | 0.82 | 0.69 | ||
*
v 2-6.
†
v 7.