Table 2.
p53 Mutation Analysis of Noninvasive Tubal Lesions and Remote Tumors
| Case | Classification | Epithelium | Base Change | Designation | Codon | Effect | OVCA | Total Citations |
|---|---|---|---|---|---|---|---|---|
| 1 | PPSC | Normal | None | None | 275 | Missense | 3 | 47 |
| STIC | c.824G > T | C275F | ||||||
| Omentum | c.824G > T | C275F | ||||||
| 2 | PPSC | Normal | None | None | 241 | Missense | 3 | 37 |
| STIC | c.722C > G | S241C | ||||||
| Omentum | c.722C > G | S241C | ||||||
| 3 | PPSC | Normal | None | None | 306 | Missense | 11 | 162 |
| STIC | c.916C > T | R306X | ||||||
| Omentum | c.916C > T | R306X | ||||||
| 4 | PPSC | Normal | None | None | 195 | Missense | 20 | 92 |
| STIC | c.584T > C | I195T | ||||||
| Peritoneum | c.584T > C | I195T | ||||||
| 5 | PPSC | Normal | None | None | — | Missense | 2 | 19 |
| P53 Sig | c.434T > C | L145P | 145 | |||||
| Peritoneum | c.434T > C | L145P |
NOTE. Data adapted (http://www.umd.be:2072/IFAMTP53A.shtml).
Abbreviations: PPSC, primary peritoneal serous carcinoma; STIC, serous tubal intraepithelial carcinoma; OVCA, reported number of ovarian cancers with this mutation.