Table 2.

Summary of Outcome Information (n = 2,882)

Parameter	Arm		No.
	A (AT)	B (AC)
Breast recurrence
Ipsilateral	22	24	46
Locoregional	39	38	77
Distant	125	128	253
Contralateral invasive breast cancer
Isolated	26	27	53
And other site	4	3	7
Total*	216	220	436
Deaths	116	123	239
Without recurrence	41	42	83
Total	157	165	322
Nonbreast second primaries
Isolated	57	39	96
And recurrence	14	13	27
Total	71	52	123†
Contralateral in situ breast cancer
Isolated	6	6	12‡
And other site (melanoma)	1	0	1‡

Abbreviations: AT, doxorubicin and docetaxel; AC, doxorubicin and cyclophosphamide; DFS, disease-free survival.

^*Only first recurrence events were collected.

^†Among 114 patients.

^‡One of these 13 died and was counted as an event in the DFS analysis. The other 12 were censored in the DFS analysis at date last known to be alive.