Fig. 4.

ΔF/F (where F is fluorescence) line scan images from intact dedifferentiating adult mouse muscle fibers. Above each ΔF/F image is the mean temporal profile centered at the peak ΔF/F. These records represent a sampling of the various different time courses of local Ca²⁺ release events recorded from dedifferentiating fibers using line scan imaging. A, B, and F: line scan images and time courses of both rapidly rising and decaying fluorescence signals. Note that these signals are quite similar to Ca²⁺ sparks observed in frog and mammalian myofibers. C, D, and E: line scan images and time courses of slower rising and decaying events. Note that these records are similar to Ca²⁺ signals as seen in developing mammalian myofibers.