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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Br J Haematol. 2008 Aug 28;143(3):395–403. doi: 10.1111/j.1365-2141.2008.07365.x

Table III.

Risk factors for mortality, relapse, and non-relapse mortality in univariate analysis*

Outcome Variable HR (95% CI) P
Mortality Lines of treatment before HCT**
≥ 4 lines of treatment before HCT		 0.71 (0.47-1.07)
0.29 (0.11-0.80)		 0.10
0.02
Chemosensitive disease 0.17 (0.06-0.47) 0.001
IPI** 1.83 (1.15-2.93) 0.01
Relapse Age** 0.68 (0.45-1.07) 0.08
Chemosensitive disease 0.20 (0.07-0.63) 0.009
NRM Lines of treatment before HCT**
≥ 4 lines of treatment before HCT		 0.61 (0.31-1.22)
0.05 (0.005-0.46)		 0.14
0.002
Chemosensitive disease 0.23 (0.05-1.02) 0.07
*

Also tested were donor type (related vs. unrelated) and prior autologous hematopoietic cell transplantation. Abbreviations: HR, hazard ratio; CI, confidence interval; HCT, hematopoietic cell transplantation; IPI, International Prognostic Index; NRM, non-relapse mortality.

**

Modelled as a continuous linear variable. HR represents increase in hazard with each increase of 1 line of treatment, 1 point in IPI, or 10 years of age.