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. 2009 Feb 28;44(2):131–141. doi: 10.3164/jcbn.08-217

Table 2.

Effect of DSS challenge or diet on anthropometric and oral intake dataa

DSS Treatmentb
 Dietc
 DSS × Dietd
DSS+ DSS− p ZD PF ZT C ZS p p
Final body weight (g) 244 ± 6 256 ± 7 0.0003 208 ± 4c 230 ± 5b 225 ± 5b 295 ± 4a 294 ± 6a <0.0001 NS
Feed intake before DSS challenge (g) 419 ± 9 417 ± 9 NS 380 ± 10b 390 ± 11b 378 ± 10b 474 ± 10a 468 ± 6a <0.0001 NS
Feed intake after DSS challenge (g) 51 ± 3 68 ± 4 <0.0001 46 ± 3b 41 ± 2b 69 ± 8a 69 ± 6a 72 ± 5a <0.0001 NS
Water intake (g) 118 ± 7 124 ± 9 NS 110 ± 9b 94 ± 5b 113 ± 7b 151 ± 8a 139 ± 8a <0.0001 NS
Water intake (g/g body weight) 0.48 ± 0.02 0.48 ± 0.02 NS 0.52 ± 0.04a 0.4 ± 0.02b 0.51 ± 0.03a 0.51 ± 0.03a 0.48 ± 0.03ab 0.0464 NS
Small intestine weight (g) 9.61 ± 0.32 8.02 ± 0.30 <0.0001 6.96 ± 0.37c 7.58 ± 0.47c 8.81 ± 0.37b 10.07 ± 0.33a 10.64 ± 0.43a <0.0001 NS
Small intestine weight (g/g body weight) 0.0393 ± 0.0008 0.0312 ± 0.0007 <0.0001 0.0332 ± 0.0013b 0.0330 ± 0.0019b 0.0392 ± 0.0015a 0.0343 ± 0.0013b 0.0364 ± 0.0015ab 0.0006 NS
Small intestine length (cm) 52.7 ± 0.6 52.2 ± 0.7 NS 49.5 ± 0.5b 51.6 ± 0.9b 49.4 ± 0.8b 55.3 ± 0.7a 56.4 ± 0.9a <0.0001 NS
Colon weight (g) 1.71 ± 0.07 2.22 ± 0.08 <0.0001 1.83 ± 0.14 2.14 ± 0.12 2.03 ± 0.14 1.8 ± 0.11 2.03 ± 0.16 NS NS
Colon weight (g/g body weight) 0.0072 ± 0.0004 0.0089 ± 0.0004 0.0004 0.0089 ± 0.0006a 0.0094 ± 0.0005a 0.0090 ± 0.0005a 0.0061 ± 0.0003b 0.0068 ± 0.0005b <0.0001 NS
Colon length (cm) 13.7 ± 3.1 12.9 ± 0.3 NS 10.8 ± 0.4 12.1 ± 0.5 11.7 ± 0.6 11.7 ± 0.5 12.5 ± 0.5 NS NS

aValues are means ± SEM, significant p values <0.05.

bDSS Challenge: DSS− = no dextran sulfate sodium challenge, DSS+ = 5% dextran sulfate sodium challenge, n = 40/group.

cDiet: ZD = zinc deficient (3 mg/kg zinc), PF = pair fed (30 mg/kg zinc) to match energy intake of ZD group, ZT = zinc deficient (3 mg/kg zinc) and repleted (300 mg/kg zinc), C = control (30 mg/kg zinc), ZS = zinc supplemented (300 mg/kg zinc), n = 16/group.

dInteraction effects of DSS challenge × diet were not significant, therefore the data are presented as main effects for DSS Treatment and Diet.