Table 3.

Effect of DSS challenge or diet on complete blood count of rats^a

	DSS Challengeb			Dietc						DSS × Dietd
	DSS+	DSS−	p	ZD	PF	ZT	C	ZS	p	p
RBC (1012/L)	6.64 ± 0.15	6.94 ± 0.10	0.0393	7.61 ± 0.11a	7.19 ± 0.14a	6.45 ± 0.20b	6.43 ± 0.11b	6.31 ± 0.17b	<0.0001	NS
Hemoglobin (g/L)	138 ± 3	146 ± 2	0.0069	157 ± 3a	148 ± 4a	133 ± 4b	139 ± 2b	132 ± 4b	<0.0001	NS
Hematocrit (L)	0.464 ± 0.009	0.472 ± 0.009	NS	0.507 ± 0.013a	0.486 ± 0.010ab	0.431 ± 0.015c	0.471 ± 0.013ab	0.45 ± 0.014bc	0.0009	NS
MCV (109/L)	69.5 ± 0.8	68.2 ± 0.4	0.0584	66.9 ± 0.5b	67 ± 0.6b	67.2 ± 0.4b	72.7 ± 1.1a	70.6 ± 1.1a	<0.0001	NS
MCH (109/L)	20.7 ± 0.1	21 ± 0.1	0.0324	20.7 ± 0.2b	20.7 ± 0.2b	20.6 ± 0.2b	21.5 ± 0.1a	21 ± 0.2b	0.0009	NS
MCHC (109/L)	298.8 ± 2.2	308.8 ± 1.3	<0.0001	308.9 ± 2.0a	308.6 ± 2.5a	306.3 ± 2.3a	296.8 ± 3.4b	297.9 ± 3.8b	0.0007	NS
WBC (109/L)	22.7 ± 1.3	12.7 ± 0.7	<0.0001	16.7 ± 1.9	15.7 ± 2.5	17.7 ± 2.3	17.1 ± 1.7	20.9 ± 2.0	NS	NS
Lymphocytes (109/L)	17.9 ± 1.2	11.1 ± 0.7	<0.0001	14.3 ± 1.5ab	12.4 ± 2.3b	12.2 ± 1.5b	16.2 ± 1.2ab	17.7 ± 1.9a	0.0352	NS
Neutrophils(109/L)	3.74 ± 0.24	1.18 ± 0.26	<0.0001	2.28 ± 0.52	2.84 ± 0.73	2.47 ± 0.52	2.07 ± 0.41	2.57 ± 0.40	NS	NS
Monocytes (109/L)	0.46 ± 0.01	0.30 ± 0.05	NS	0.34 ± 0.08	0.16 ± 0.07	0.42 ± 0.14	0.5 ± 0.14	0.49 ± 0.15	NS	NS
Platelets (109/L)	717 ± 20	778 ± 25	NS	759 ± 33	771 ± 42	661 ± 37	766 ± 23	792 ± 38	NS	NS

^aValues are means ± SEM, significant p values <0.05.

^bDSS Challenge: DSS– = no dextran sulfate sodium challenge, DSS+ = 5% dextran sulfate sodium challenge, n = 40/group.

^cDiet: ZD = zinc deficient (3 mg/kg zinc), PF = pair fed (30 mg/kg zinc) to match energy intake of ZD group, ZT = zinc deficient (3 mg/kg zinc) and repleted (300 mg/kg zinc), C = control (30 mg/kg zinc), ZS = zinc supplemented (300 mg/kg zinc), n = 16/group.

^dInteraction effects of DSS challenge × diet were not significant, therefore the data are presented as main effects for DSS Treatment and Diet