Table 3-2.
Characteristics of subjects by urinary 8-OHdG (ng/mg creatinine)
| Variable | All (n = 677) |
Male (n = 293) |
Female (n = 384) |
|||
|---|---|---|---|---|---|---|
| mean ± SE | p | mean ± SE | p | mean ± SE | p | |
| Total | 8.43 ± 0.01 | — | 8.18 ± 0.01 | — | 8.63 ± 0.01 | 0.086$ |
| Age (year) | ||||||
| <40 | 7.91 ± 0.01 | <0.001** | 7.76 ± 0.01 | 0.021* | 8.01 ± 0.01 | 0.003** |
| ≥40 | 8.90 ± 0.01 | 8.53 ± 0.01 | 9.20 ± 0.01 | |||
| BMI (kg/m2) | ||||||
| <18.5 | 8.63 ± 0.02 | 0.135 | 9.68 ± 0.05 | 0.107 | 8.37 ± 0.03 | 0.285 |
| 18.5–24.9 | 8.56 ± 0.01 | 8.21 ± 0.01 | 8.83 ± 0.01 | |||
| ≥25.0 | 7.90 ± 0.02 | 7.83 ± 0.02 | 7.98 ± 0.03 | |||
| Smoking | ||||||
| Never | 8.35 ± 0.01 | 0.377 | 7.98 ± 0.01 | 0.330 | 8.48 ± 0.01 | 0.109 |
| Smokers | 8.59 ± 0.01 | 8.31 ± 0.01 | 9.41 ± 0.02 | |||
| Alcohol drinking (units/week) | ||||||
| No | 8.49 ± 0.01 | 0.778 | 7.91 ± 0.02 | 0.448 | 8.73 ± 0.01 | 0.852 |
| <20 | 8.43 ± 0.01 | 8.31 ± 0.01 | 8.54 ± 0.01 | |||
| ≥20 | 7.99 ± 0.03 | 7.72 ± 0.03 | 9.29 ± 0.09 | |||
| Exercise (times/week) | ||||||
| No | 8.59 ± 0.01 | 0.229 | 8.16 ± 0.01 | 0.912 | 8.82 ± 0.01 | 0.059 |
| 1-5 | 8.15 ± 0.01 | 8.23 ± 0.01 | 8.05 ± 0.02 | |||
| 6 or over | 8.82 ± 0.03 | 7.96 ± 0.03 | 10.63 ± 0.04 | |||
*p<0.05, **p<0.01 (gender, age, and smoking by Unpaired t test; BMI, alcohol drinking, and exercise by ANOVA)
$p value by Unpaired t test to test gender differences
log-transformed data in urinary 8-isoprostane and 8-OHdG