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. 2009 Mar 18;4(3):e4857. doi: 10.1371/journal.pone.0004857

Figure 6. Higher viral load is detected in DBA/2J mice compared to C57BL/6J mice.

Figure 6

DBA/2J and C57BL/6J mice were infected intra-nasally with 2×103 FFU and viral load was determined at the indicated times post inoculation for infectious particles measured by foci assay (A) or by copy number of viral hemagglutinin (HA) RNA (B). Mean +/− SEM are shown. For foci assay in (A), 9 DBA/2J mice were used at all time points, and for C57BL/6J, 6 mice were used at day1, 8 mice at day 2 and 9 mice at days 3, 4, and 8. For RNA assays in (B), 10 mice were used except 15 for day 4, and 5 for day 6. DBA/2J and C57BL/6J mice were compared for statistical significant differences using non-parametric Mann-Whitney-U-test. *: p value<0.05; **: p<0.01; ***: p value<0.001.