Table 1.
Baseline patient and tumor characteristics of pulmonary metastasectomies performed from January 1986 to November 2006
| All (n = 171) | OPEN (n = 135) | VATS (n = 36) | p-value† | |
| Age (in years)* | < 0.01† | |||
| Median (Interquartile range) | 53 (43–63) | 49 (40–61) | 58.5 (50.5–71) | |
| 95% C.I. | 49 to 56 | 47 to 55.25 | 52.85 to 66.29 | |
| Sex | 0.26 | |||
| Female | 71 (41.5) | 53 (39.3) | 18 (50) | |
| Male | 100 (58.5) | 82 (60.7) | 18 (50) | |
| Race | 0.06 | |||
| Caucasian | 140 (81.9) | 112 (83.0) | 28 (78) | |
| non-Caucasian | 31 (18.1) | 23 (17) | 8 (22) | |
| Comorbidities | ||||
| Single | 61 (35.7) | 45 (33.3) | 16 (44) | 0.24 |
| 3 comorbidities | 10 (5.8) | 5 (3.7) | 5 (14) | 0.04† |
| Smoker | 62 (36.3) | 47 (34.8) | 15 (41.7) | 0.44 |
| Primary Tumor Type | < 0.01† | |||
| Bladder | 3 (1.8) | 2 (1.5) | 1 (3) | |
| Breast AC | 9 (5.3) | 5 (3.7) | 4 (11) | |
| Colorectal AC | 26 (15.2) | 14 (10.4) | 12 (33) | |
| Head/Neck | 4 (2.3) | 3 (2.2) | 1 (3) | |
| Melanoma | 14 (8.2) | 6 (4.4) | 8 (22) | |
| Renal cell | 22 (12.9) | 21 (15.6) | 1 (3) | |
| Sarcoma | 81 (47.4) | 73 (54.1) | 8 (22) | |
| Testicular | 5 (2.9) | 5 (3.7) | - | |
| Other | 7 (4.1) | 6 (4.4) | 1 (3) | |
| Adjuvant therapy | ||||
| Chemotherapy | 129 (75.4) | 106 (78.5) | 23 (64) | 0.08 |
| Radiation | 73 (42.7) | 54 (40) | 19 (53) | 0.19 |
| Laterality | < 0.01† | |||
| Unilateral | 124 (72.5) | 90 (66.7) | 34 (94) | |
| Bilateral | 47 (27.5) | 45 (33.3) | 2 (6) | |
| Magnitude | 0.06 | |||
| Wedge resection | 118 (69) | 88 (65.2) | 30 (83) | |
| All other | 53 (31) | 47 (34.8) | 6 (16.7) | |
| Number of lesions | < 0.01† | |||
| Single | 48 (28.1) | 28 (20.7) | 20 (56) | |
| 2–5 | 94 (55) | 79 (58.5) | 15 (42) | |
| > 5 | 29 (17) | 28 (20.7) | 1 (3) | |
| Metastatic Occurrences | 0.15 | |||
| 1 | 102 (59.6) | 76 (56.3) | 26 (72) | |
| 2 | 38 (22.2) | 31 (23) | 7 (19) | |
| 3+ | 31 (18.1) | 28 (20.7) | 3 (8) | |
| Deaths | 74 (43) | 65 (48) | 9 (25) | 0.02† |
*All characteristics are expressed as no. (%), unless specified otherwise. Some covariables were grouped to preserve a 10% number of patients in each category for analysis. Non-Caucasian includes: Asian (10 OPEN; 7 VATS), Black (4 OPEN; 1 VATS) and Latino (9 OPEN; 0 VATS). All other includes: segmentectomy (17 OPEN; 4 VATS), lobectomy (29 OPEN; 2 VATS) and pneumonectomy (1 OPEN; 0 VATS). When PTT was categorized into carcinoma (includes bladder, breast, colorectal, melanoma, head/neck, renal cell, testicular, and 3 other type) and sarcoma (includes sarcoma and 3 other type), a statistical difference remained (p < 0.001). † Pearson χ2 or Fisher exact; two-tailed p-value < 0.05 considered statistically significant.