Table 2.
GA of Rat | n | SD, μm* | AC, dB/mm3† | SSF, dB/mm3‡ | Hydroxyproline/Cervix, %§ | Hydroxyproline/Cervix, μg/mg|| | Water/Cervix, % | Ratio of Collagen Pixels¶ |
---|---|---|---|---|---|---|---|---|
Nonpregnant | 13 | 10.4 (0.6)# | −118 (6)#** | 2.8 (1)#** | 0.88 (0.1)#** | 568 (75)#** | 68 (5) | 0.83 (0.3) |
Day 15 | 13 | 8.2 (1.3)#** | −130 (7)** | −1.5 (1) | 0.72 (0.1)#** | 532 (83)** | 69 (8) | 0.69 (0.3) |
Day 17 | 13 | 11.2 (0.8)# | −144 (7)# | −2.3 (2) | 0.68 (0.1) | 603 (103) | 68 (5) | 0.61 (0.2) |
Day 19 | 13 | 8.6 (1.2) | −130 (5)** | −1.2 (1) | 0.62 (0.1)# | 605 (75)# | 69 (6) | 0.69 (0.2) |
Day 20 | 13 | 8.8 (1.0) | −136 (8) | −2.2 (2) | 0.64 (0.1)# | 640 (131)# | 69 (4) | 0.58 (0.2) |
Day 21 | 13 | 10.0 (1.7)# | −141 (11)# | −2.7 (2) | 0.62 (0.1)# | 707 (153)# | 68 (6) | 0.70 (0.3) |
Statistic | F5,72 = 10.72; P < .0001 | F5,72 = 19.47; P < .0001 | F5,72 = 26.47; P < .0001 | F5,72 = 107.45; P < .0001 | F5,72 = 4.09; P < .003 | F5,72 = 0.24; P = .24 | F5,72 = 1.6; P = .17 |
Values are expressed as mean (standard deviation)
Scatterer diameter = correlational length of the scatterer; differences among groups.
Acoustic concentration = number of scatterers/mm3 − (average impedance of scatterers)2.
Scatterer Strength Factor = AC × (average radius of scatterers)6.
Concentration of hydroxyproline per cervix, wet weight.
Content of hydroxyproline per total cervix, wet weight.
Ratio of collagen-stained pixels compared with stained cells (smooth muscles and white cells) per digital histologic slide at ×20 magnification.
Tukey post hoc tests to determine between-group differences:
P < .01 versus day 15 group;
P < .01 versus day 21 group.