Table 1.
Demographic and Behavioral Data.
| MCI | Controls | ||||
|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||
| Age | 73.4 | 7.1 | 74.4 | 6.4 | |
| Education | 16.6 | 2.4 | 15.7 | 2.8 | |
| Gender | 8m/8f | 7m/9f | |||
| MMSE | 27.4 | 2.2 | 29.7 | 0.4 | ** |
| WRAT-III Reading (standard scorea) | 112 | 5.8 | 110 | 7.1 | |
| RAVLT total (scaled scorea) | 6.3 | 4.0 | 12.3 | 3.3 | ** |
| RAVLT delayed recall (scaled scorea) | 6.9 | 2.2 | 11.6 | 1.8 | ** |
| BVMT-R total (trials 1–3 T scorea) | 33.9 | 8.2 | 56.9 | 10.0 | ** |
| BVMT-R delayed recall (T scorea) | 31.7 | 9.0 | 55.8 | 7.9 | ** |
| Trail Making Test A (scaled scorea) | 9.9 | 2.1 | 11.5 | 2.2 | |
| Trail Making Test B (scaled scorea) | 9.6 | 2.9 | 13.2 | 2.3 | * |
| Boston Naming Test (scaled scorea) | 12.1 | 2.2 | 13.6 | 2.9 | |
| Animal Naming (scaled scoreb) | 8.3 | 3.1 | 10.6 | 2.9 | * |
| COWAT (scaled scorea) | 10.9 | 2.4 | 12.4 | 1.9 | * |
| JLO (scaled scorea) | 12.8 | 2.7 | 13.1 | 2.3 | |
| IQCODE informant form | 3.8 | 0.5 | 2.9 | 0.3 | ** |
| IQCODE patient form | 3.2 | 0.7 | 3.1 | 0.2 | |
| IQCODE discrepancy | 0.6 | 0.7 | −0.1 | 0.3 | ** |
| Functional MRI Task : | |||||
| Self condition RT (milliseconds) | 1689 | 240 | 1747 | 182 | |
| Self condition % “Yes” responses | 49.7 | 6.2 | 48.4 | 4.4 | |
| Semantic condition RT (milliseconds) | 1737 | 261 | 1792 | 194 | |
| Semantic condition % “Yes” responses | 46.5 | 7.1 | 48.6 | 4.2 | |
p < .001
p < .05 statistical significance between MCI and control groups
score is age-corrected
score is age- and education-corrected.
MCI = Mild Cognitive Impairment; MMSE = Mini Mental State Exam; WRAT-III = Wide Range Achievement Test, 3rd Edition; RAVLT = Rey Auditory Verbal Learning Test; BVMT-R = Brief Visuospatial Memory Test, Revised; COWAT = Controlled Oral Word Association Test; JLO = Judgement of Line Orientation; IQCODE = Informant Questionnaire on Cognitive Decline in the Elderly; RT = reaction time