Table 2.
Licking measures across tastant and drug conditions
| Measure | Water | 0.1 m sucrose | 1 m sucrose | ANOVA
|
|||||
|---|---|---|---|---|---|---|---|---|---|
| aCSF | 3V ORXA | aCSF | 3V ORXA | aCSF | 3V ORXA | Drug F(1,15) (P) | Concentration F(2,30) (P) | Interaction F(2,30) (P) | |
| 90-min intake (ml) | 2.78 ± 0.62 | 4.92 ± 1.16 | 13.19 ± 2.03 | 21.21 ± 3.30 | 10.39 ± 0.96 | 15.13 ± 1.46 | 33.75 (0.001) | 21.13 (0.001) | 5.65 (0.008) |
| Meals initiated | 1.25 ± 0.11 | 2.13 ± 0.29 | 1.50 ± 0.24 | 2.06 ± 0.25 | 1.13 ± 0.09 | 2.38 ± 0.20 | 43.95 (0.001) | 0.12 (NS) | 1.25 (NS) |
| Meal lick count | 426 ± 121 | 630 ± 202 | 2122 ± 286 | 2957 ± 412 | 1635 ± 144 | 1802 ± 170 | 8.62 (0.01) | 22.66 (0.001) | 5.38 (0.01) |
| Latency (sec) | 98.4 ± 35.5 | 464.8 ± 232.8 | 18.5 ± 4.5 | 296.8 ± 268.9 | 9.40 ± 1.7 | 9.3 ± 1.1 | 1.89 (NS) | 2.65 (NS) | 1.48 (NS) |
| First minute lick rate | 96 ± 35 | 187 ± 42 | 272 ± 28 | 272 ± 24 | 286 ± 19 | 287 ± 17 | 2.10 (NS) | 12.70 (0.001) | 2.43 (NS) |
| Mean burst size (licks) | 44.4 ± 9.9 | 52.8 ± 9.8 | 67.9 ± 10.8 | 71.6 ± 7.5 | 98.1 ± 12.7 | 91.5 ± 11.3 | 0.17 (NS) | 8.80 (0.001) | 0.49 (NS) |
| Mean lick rate (licks/min) | 150.0 ± 32.6 | 157.0 ± 28.4 | 115.5 ± 15.3 | 118.3 ± 19.0 | 204.9 ± 17.9 | 184.8 ± 16.8 | 0.07 (NS) | 5.02 (0.006) | 0.40 (NS) |
| Mean pause duration (sec) | 49.1 ± 16.1 | 34.9 ± 8.1 | 24.0 ± 3.0 | 28.7 ± 5.2 | 16.2 ± 1.6 | 20.0 ± 5.0 | 0.18 (NS) | 6.40 (0.01) | 0.66 (NS) |
| Pause time (%) | 63.8 ± 8.6 | 56.8 ± 9.5 | 70.4 ± 3.7 | 68.6 ± 5.4 | 51.2 ± 4.2 | 54.0 ± 4.5 | 1.03 (NS) | 2.57 (NS) | 0.51 (NS) |
| Lick volume (μl) | 7.56 ± 1.13 | 7.97 ± 1.87 | 5.70 ± 0.18 | 5.97 ± 0.52 | 6.16 ± 0.24 | 5.93 ± 0.23 | 0.008 (NS) | 4.04 (0.03) | 0.01 (NS) |
| Within-burst lick rate (licks/sec) | 5.2 ± 0.4 | 5.5 ± 0.3 | 6.3 ± 0.1 | 6.4 ± 0.1 | 6.4 ± 0.1 | 6.5 ± 0.1 | 1.21 (NS) | 12.19 (0.001) | 0.29 (NS) |
| Mean ILI (0–249 msec) | 150.5 ± 6.77 | 145.4 ± 2.5 | 144.8 ± 2.1 | 146.0 ± 3.1 | 146.3 ± 2.4 | 145.8 ± 2.3 | 0.35 (NS) | 0.34 (NS) | 0.63 (NS) |
| ILI% (0–249 msec) | 81.2 ± 6.5 | 88.2 ± 4.4 | 96.3 ± 0.7 | 97.4 ± 0.5 | 96.5 ± 1.2 | 97.2 ± 0.8 | 1.26 (NS) | 9.67 (0.001) | 0.60 (NS) |
Results are shown as mean ± se. Statistical significance was set at P≤ 0.05. Significant F/P ANOVA values appear in boldface. ILI%, Proportion of ILIs in the range indicated relative to the total of all ILIs less than 1 sec.