Table 1.
Effects of intrameal HPV GLP-1 infusions during the first spontaneous meal of the dark on meal duration, satiety ratio, and cumulative food intake
| GLP-1 dose (nmol/kg)
|
||||
|---|---|---|---|---|
| 0 | 0.33 | 1.0 | 3.0 | |
| Meal duration (min) | 9 ± 1.1 | 8 ± 1.3 | 5 ± 0.5a | 4 ± 0.4a |
| Satiety ratio (min/g) | 47.9 ± 6.2 | 55.6 ± 6.0 | 66.2 ± 9.7 | 51.6 ± 14.0 |
| Cumulative food intake (g) | ||||
| 2 h | 3.0 ± 0.2 | 3.6 ± 0.3 | 3.2 ± 0.4 | 2.7 ± 0.4 |
| 4 h | 6.7 ± 0.3 | 6.7 ± 0.1 | 6.5 ± 0.3 | 5.6 ± 0.6 |
| 6 h | 10.3 ± 0.5 | 11.1 ± 0.4 | 11.1 ± 0.4 | 10.4 ± 0.9 |
| 22 h | 25.4 ± 0.7 | 23.5 ± 0.3 | 23.7 ± 1.0 | 22.9 ± 1.2 |
Meal durations are means ± sem from 11 rats.
a
Different from zero value, Bonferroni-Holm test (38) after significant ANOVA (F3/22 = 5.47; P < 0.01).