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. Author manuscript; available in PMC: 2010 Feb 15.
Published in final edited form as: Biol Psychiatry. 2008 Oct 19;65(4):319–328. doi: 10.1016/j.biopsych.2008.08.035

Figure 3.

Figure 3

Western blots showing the immunolabeling of TrkA, TrkC, p75NTR and β-actin in PFC (a) and hippocampus (b) of 3 normal controls and 3 suicide subjects and the mean ± S.D. of immunolabeling of TrkA, TrkC, or p75NTR in PFC (c) and hippocampus (d) from normal controls and suicide subjects. Protein samples were subjected to 10% polyacrylamide gel electrophoresis and transferred to ECL-nitrocellulose membranes, which were then incubated with primary antibody specific for TrkA, TrkC, p75NTR, or β-actin and corresponding secondary antibody. The bands were quantified as described in Methods. Ratios of the optical density of TrkA, TrkC, or p75NTR to that of β-actin were calculated. PFC samples were from 21 normal controls and 28 suicide subjects; hippocampus samples were from 21 normal controls and 26 suicide subjects. Suicide group was compared with control group.* Overall ANCOVA: PFC: TrkA, df = 1,42, F = 20.1, P <0.001; TrkC, df = 1,42, F = 0.001, P = 0.98; p75NTR, df = 1,42, F = 18.9, P <0.001; hippocampus: TrkA, df = 1,40, F = 21.7, P <0.001; TrkC, df = 1,40, F = 40.3, P <0.001; p75NTR, df = 1,40, F = 13.9, P = 0.001. *P = 0.001, ** P <0.001.