Table 2.

 Serious maternal adverse events associated with tocolytic treatment

Serious adverse event	Tocolytic	No of fetuses	Intensive care	Causality
Dyspnoea	Ritodrine	1	No	Probable
Dyspnoea	Fenoterol	1	No	Probable
Dyspnoea	Atosiban, nifedipine, and ritodrine*	1	No	Probable
Dyspnoea	Fenoterol	1	No	Probable
Dyspnoea	Nifedipine	2	No	Possible
Dyspnoea	Atosiban and fenoterol*	1	Yes	Possible
Hypotension	Nifedipine	1	No	Probable
Hypotension	Nifedipine	1	No	Certain
Hypotension	Nifedipine	2	No	Certain
Hypotension	Nifedipine	1	No	Certain
Cardiac failure	Atosiban then fenoterol†	1	Yes	Possible
Hypoxia	Nifedipine and ritodrine*	2	No	Probable
Lung oedema	Atosiban, nifedipine, and fenoterol*	2	Yes	Possible
Lung oedema	Atosiban and nifedipine*	1	Yes	Probable
Dyspnoea	Fenoterol	1	No	Unlikely
Deep vein thrombosis	Ritodrine then nifedipine†	2	No	Unlikely

*Combined courses: event occurred after simultaneous administration of all indicated tocolytics.

^†Sequential courses: event occurred after administration of second tocolytic.