Table 3.
Hazard ratio (HR) and 95% confidence intervals of total mortality for physical activity level in leisure time, smoking, and obesity status using time updated and baseline data
| Exposure and category | Time at risk (person years) | No of deaths | Hazard ratio (95% CI) | ||
|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 3 | |||
| Time updated model* | |||||
| Physical activity: | |||||
| High | 28 790 | 531 | 1.00† | 1.00† | 1.00† |
| Medium | 25 371 | 600 | 1.32 (1.18 to 1.49) | 1.24 (1.10 to 1.39) | 1.22 (1.08 to 1.37) |
| Low | 7306 | 198 | 1.75 (1.48 to 2.06) | 1.41 (1.19 to 1.67) | 1.40 (1.18 to 1.66) |
| Smoking status: | |||||
| Never | 20 657 | 465 | 1.00† | 1.00† | 1.00† |
| Former | 19 420 | 373 | 1.18 (1.02 to 1.36) | 1.15 (1.00 to 1.32) | 1.10 (0.96 to 1.27) |
| Current | 21 389 | 491 | 2.09 (1.82 to 2.39) | 1.98 (1.72 to 2.28) | 1.90 (1.64 to 2.19) |
| Obesity status: | |||||
| Non-obese | 56 620 | 1157 | 1.00† | 1.00† | 1.00† |
| Obese | 4847 | 172 | 1.52 (1.29 to 1.78) | 1.49 (1.19 to 1.86) | 1.51 (1.21 to 1.90) |
| Baseline model‡ | |||||
| Physical activity: | |||||
| High | 30 930 | 617 | 1.00† | 1.00† | 1.00† |
| Medium | 21 850 | 504 | 1.20 (1.07 to 1.35) | 1.16 (1.03 to 1.31) | 1.14 (1.01 to 1.28) |
| Low | 8687 | 213 | 1.30 (1.12 to 1.52) | 1.14 (0.98 to 1.34) | 1.13 (0.96 to 1.33) |
| Smoking status: | |||||
| Never | 16 626 | 266 | 1.00† | 1.00† | 1.00† |
| Former | 15 446 | 291 | 1.21 (1.03 to 1.43) | 1.22 (1.03 to 1.44) | 1.20 (1.01 to 1.41) |
| Current | 29 395 | 777 | 1.87 (1.63 to 2.16) | 1.88 (1.63 to 2.17) | 1.94 (1.67 to 2.24) |
| Obesity status: | |||||
| Non-obese | 58 032 | 1220 | 1.00† | 1.00† | 1.00† |
| Obese | 3434 | 114 | 1.81 (1.50 to 1.20) | 1.30 (1.01 to 1.68) | 1.26 (0.97 to 1.62) |
Model 1 includes one exposure only. Model 2 includes physical activity, smoking status, and obesity status; and as covariates height and weight (both continuous); self perceived health (not good, good); physical activity at work (sedentary, light, medium, high, unknown, unemployed); diabetes mellitus and any musculoskeletal, neurological, or psychiatric disorders (yes, no for each disorder); and alcohol use (abstainer, normal, suspected alcohol dependence). Model 3 as for model 2 but with addition of systolic and diastolic blood pressure, use of antihypertensive drugs, total serum cholesterol concentrations, educational level, and socioeconomic group.
*Based on time updated data and mortality follow-up.
†Reference category.
‡Based on baseline data and mortality follow-up.