Table 3.

Modafinil’s effects on working memory and memory

			Neurocognitive measures						Modafinil effect
Test name	Abbrev	Working memory	Attention/impulse control	Memory	Frontal lobe function	Speed	+ Accuracy	−Accuracy	+ Speed	− Speed	No Effect
Working memory tests							1,2,8,9		11b	1,8,9,11	1,2,4,6,10c,2
Digit Span		■					1,8,9				12
Spatial Working memory	SWM	■									1
Tower of London	TOL	■			■		1		11b	1,8,9,11	3,4
Numeric Working Memory	NWM	■					2
Letter Number Sequencing	LNS	■									6,10c
Occulomotor Delayed Response	ODR	■									10°
MemoryTests							1,2,7		2	1,9	1,3,4,8,10c,1
Digit Recall	DRT			■			7
Repeated Acquisition	RAT			■			7
Pattern Recognition Memory	PRM			■			1				8
Paired Associates Learning	PAL			■
Delayed Matching to Sample	DMS			■		■	2		2	1,9	3,10c,11
Spatial Span	SSP			■							1
Visuospatial Delayed Matching	VSD			■
Logical memory	LMT			■							3,4,11
Digit Symbol Substitution	DSS			■			7				6

1) Turner et al (2003), 2) Muller et al (2004), 3) Randall et al (2003), 4) Randall et al (2004), 5) Randall et al (2005), 6) Walsh et al (2004), 7) Hart et al (2005), 8) Turner et al (2004b), 9) Turner et al (2004a), 10) Sevy et al (2005), 11) Randall et al (2005), 12) Chan et al (2006), 13) Gill et al (2006), 14) Killgore et al (2006)

^aimprovement for lower IQ subjects,

^b400 mg dose showed effect,

^cSchizophrenic subjects controlled with atypical antipsychotics.