Figure 1.
CYP2D6-related therapeutic response in Alzheimer’s disease. Cognitive performance in extensive (EM), intermediate (IM), poor (PM), and ultra-rapid metabolizers (UM) during treatment with a multifactorial (combination) therapy.
Notes and abbreviations: MMSE, Mini-Mental State Examination; 0, Baseline Score (prior to treatment); 1–12, 1–12 months of treatment; SD, standard deviation; X, mean (MMSE score).