Table 2.
Factor | No. (%) | % with hypercoagulability | P |
Hypercoagulability | |||
No | 173 (60) | - | - |
Yes | 116 (40) | - | - |
Extent of hypercoagulability | |||
Low | 13 (11) | - | - |
Intermediate | 24 (21) | - | - |
High | 79 (68) | - | - |
Age | |||
< 60 | 107 (37) | 34 | |
≥ 60 | 182 (63) | 44 | .004 |
Gender | |||
Male | 224 (78) | 39 | |
Female | 65 (22) | 45 | .61 |
ECOG | |||
0 | 110 (38) | 38 | |
1 | 170 (59) | 41 | |
2 | 9 (3) | 44 | .07 |
Prior nephrectomy | |||
No | 25 (9) | 48 | |
Yes | 264 (91) | 40 | .03 |
Time from diagnosis to on-study | |||
≥ 1 y | 165 (57) | 30 | |
< 1 y | 124 (43) | 53 | < .001 |
Number of metastatic sites | |||
0, 1 | 125 (43) | 17 | |
≥ 2 | 164 (57) | 58 | .001 |
Bone metastasis | |||
No | 199 (69) | 38 | |
Yes | 90 (31) | 44 | .06 |
Liver metastasis | |||
No | 211 (73) | 34 | |
Yes | 78 (27) | 56 | .02 |
MSKCC prognostic groups | |||
Favorable | 121 (42) | 46 | |
Intermediate | 64 (22) | 22 | |
Poor | 104 (36) | 44 | .84 |
Histology | |||
Clear cell | 231 (80) | 42 | |
Non-clear | 58 (20) | 33 | .04 |
Venous thrombosis | |||
No | 275 | 37 | |
Yes | 14 | 100 | - |