Table 1.

Dosages of amphotericin B deoxycholate and characteristics of patients receiving rapid (four hours) and continuous (24 hours) infusions of the drug. Values are numbers (percentages) of patients unless stated otherwise

	Infusion rate
	Rapid (n=40)	Continuous (n=40)
Median age (range)	46 (20-75)	47 (17-74)
Median (range) No of days of treatment	12 (3-51)	16 (3-89)
Median (range) maximum daily dose (mg/kg)	0.95 (0.4-1.2)	0.96 (0.5-1.5)
Median (range) cumulative dose (mg/kg)	10.8 (2.1-42.7)	14.3 (1.8-89.0)
Male	22	27
Diagnosis:
Acute myeloid leukaemia	29 (73)	25 (63)
Acute lymphatic leukaemia	4 (10)	5 (13)
Lymphoma	4 (10)	5 (13)
Solid tumour	2 (5)	2 (5)
HIV	0	2 (5)
Others	1 (3)	1 (3)
Neutropenia (<500/μl)	36 (90)	37 (93)
Concurrent treatment:
Aminoglycosides	18 (45)	22 (55)
Vancomycin	10 (25)	11 (28)
Diuretics	18 (45)	16 (40)
Granulocyte colony stimulating factor	13 (33)	18 (45)