Table 5.

Mortality and frequency of invasive fungal infections in patients receiving rapid (four hours) or continuous (24 hours) infusions of amphotericin B deoxycholate. Values are numbers (percentages) of patients

	Infusion rate
	Rapid (n=40)	Continuous (n=40)
Proved fungal infections	3* (8)	7† (18)
Breakthrough fungaemia	0	0
Mortality:
During treatment‡	7 (18)	0
After 3 months' follow up§	12 (30)	4 (10)

^*Proved angioinvasive pulmonary mould infection with septated branching hyphae at necropsy. 

^†Cryptococcosis (two patients), systemic candidiasis (one), pulmonary aspergillosis (three), and pulmonary Rhizopus pusillus and Aspergillus fumigatus infection (one). 

^‡P=0.012, relative risk is infinity. 

^§P=0.048, relative risk (3.0, 95% confidence interval 1.1 to 8.5).